Question 1

Antimicrobials that are macrolides

Accepted Answer

A)  disrupt cell membrane function.
B)  include tetracyclines.
C)  include azithromycin,clarithromcyin,and erythromycin.
D)  are very narrow-spectrum drugs.
E)  are hepatotoxic.F) C) and D)
G) B) and D)

Question 2

Which of the following is not an aminoglycoside?

Accepted Answer

A)  streptomycin
B)  gentamicin
C)  tetracycline
D)  amikacin
E)  tobramycinF) B) and C)
G) A) and C)

Question 3

The drug that is used to treat typhoid fever and brain abscesses,but can cause aplastic anemia,is:

Accepted Answer

A)  chloramphenicol.
B)  clindamycin.
C)  ciprofloxacin.
D)  bacitracin.
E)  gentamicin.F) A) and C)
G) B) and C)

Question 4

Which of the following microbials does not inhibit DNA synthesis?

Accepted Answer

A)  chloroquine
B)  quinolone
C)  penicillin
D)  azidothymidine
E)  acyclovirF) B) and D)
G) C) and D)

Question 5

A superinfection results from

Accepted Answer

A)  build up of a drug to toxic levels in the patient.
B)  the wrong drug administered to the patient.
C)  an immune system reaction to the drug.
D)  a decrease in most normal biota resulting in the overgrowth of an unaffected species.E) C) and D)
F) B) and D)

Question 6

Which of the following is not true of polymyxins?

Accepted Answer

A)  source is Bacillus polymyxa
B)  narrow spectrum
C)  toxic to kidneys
D)  target cell walls
E)  can treat severe urinary tract infections caused by gram-negative bacilliF) A) and E)
G) All of the above

Question 7

When a patient's immune system reacts adversely to a drug,this serious side effect is called a superinfection.

Accepted Answer

A) True 
 B)False

Question 8

The drug used against intestinal anaerobic bacteria,that can also alter normal biota leading to antibiotic-associated colitis,is

Accepted Answer

A)  chloramphenicol.
B)  clindamycin.
C)  ciprofloxacin.
D)  bacitracin.
E)  gentamicin.F) All of the above
G) A) and D)

Question 9

Ciprofloxacin is used to treat viral respiratory infections.

Accepted Answer

A) True 
 B)False

Question 10

Antibiotics which disrupt prokaryotic ribosomes can also affect

Accepted Answer

A)  eukaryotic large ribosomal subunit.
B)  eukaryotic small ribosomal subunit.
C)  ribosomal RNA.
D)  eukaryotic mitochondrial ribosomes.E) B) and C)
F) A) and B)

Question 11

Who is considered to be the father of modern antibiotics?

Accepted Answer

A)  Fleming
B)  Chargaff
C)  Watson
D)  Crick
E)  DomagkF) A) and B)
G) A) and E)

Question 12

An antimicrobial with a low therapeutic index is a safer choice compared to a drug with a high therapeutic index.

Accepted Answer

A) True 
 B)False

Question 13

The first modern antimicrobial drugs were sulfa drugs.

Accepted Answer

A) True 
 B)False

Question 14

Drug toxicity occurs when an antimicrobial drug acts as antigen and stimulates an allergic response.

Accepted Answer

A) True 
 B)False

Question 15

An ideal antimicrobial therapeutic drug exhibits all of the following characteristics except

Accepted Answer

A)  nontoxic to host.
B)  easily broken down by host.
C)  easily administered.
D)  limited capacity to elicit resistance.
E)  nonallergenic.F) B) and C)
G) A) and E)

Question 16

Indwelling catheter biofilm infections are more resistant to antibiotics than nonbiofilm infections.

Accepted Answer

A) True 
 B)False

Question 17

Which two antibiotics affect nucleic acids of bacteria?

Accepted Answer

A)  tetracycline and amphotericin B
B)  trimethoprim and sulfonamides
C)  rifampin and quinolones
D)  tetracycline and bacitracin
E)  penicillin and vancomycinF) B) and E)
G) C) and D)

Question 18

The major source of naturally produced penicillin is the mold

Accepted Answer

A)  Penicillium notatum.
B)  Penicilium chrysogenum.
C)  Penicilium familiaris.
D)  Naturally produced penicillin is no longer used.E) A) and B)
F) C) and D)

Question 19

Primaquine and chloroquine are drugs used in the treatment of ___ infections.

Accepted Answer

A)  gram-positive bacterial
B)  gram-negative bacterial
C)  fungal
D)  protozoan
E)  viralF) None of the above
G) A) and E)

Question 20

All of the following pertain to cephalosporins except

Accepted Answer

A)  have a beta-lactam ring.
B)  greater resistance to beta-lactamases.
C)  newer generations have activity against gram-negative bacteria.
D)  many administered by injection,not orally.
E)  are synthetic drugs.F) A) and E)
G) A) and B)

Exam 12: Drugs, Microbes, host-The Elements of Chemotherapy

Which of the following microbials does not inhibit DNA synthesis?

Correct AnswerverifiedShow Answer

Indwelling catheter biofilm infections are more resistant to antibiotics than nonbiofilm infections.

Correct AnswerverifiedShow Answer

Antibiotics which disrupt prokaryotic ribosomes can also affect

Correct AnswerverifiedShow Answer

Which of the following is not true of polymyxins?

Correct AnswerverifiedShow Answer

Ciprofloxacin is used to treat viral respiratory infections.

Correct AnswerverifiedShow Answer

Antimicrobials that are macrolides

Correct AnswerverifiedShow Answer

The major source of naturally produced penicillin is the mold

Correct AnswerverifiedShow Answer

The drug that is used to treat typhoid fever and brain abscesses,but can cause aplastic anemia,is:

Correct AnswerverifiedShow Answer

When a patient's immune system reacts adversely to a drug,this serious side effect is called a superinfection.

Correct AnswerverifiedShow Answer

Which two antibiotics affect nucleic acids of bacteria?

Correct AnswerverifiedShow Answer

Who is considered to be the father of modern antibiotics?

Correct AnswerverifiedShow Answer

Drug toxicity occurs when an antimicrobial drug acts as antigen and stimulates an allergic response.

Correct AnswerverifiedShow Answer

Which of the following is not an aminoglycoside?

Correct AnswerverifiedShow Answer

A superinfection results from

Correct AnswerverifiedShow Answer

The drug used against intestinal anaerobic bacteria,that can also alter normal biota leading to antibiotic-associated colitis,is

Correct AnswerverifiedShow Answer

The first modern antimicrobial drugs were sulfa drugs.

Correct AnswerverifiedShow Answer

An ideal antimicrobial therapeutic drug exhibits all of the following characteristics except

Correct AnswerverifiedShow Answer

All of the following pertain to cephalosporins except

Correct AnswerverifiedShow Answer

An antimicrobial with a low therapeutic index is a safer choice compared to a drug with a high therapeutic index.

Correct AnswerverifiedShow Answer

Primaquine and chloroquine are drugs used in the treatment of ___ infections.

Correct AnswerverifiedShow Answer

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified

Correct Answer
verified