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Ampicillin,amoxicillin,mezlocillin,and penicillin G all


A) target the cell wall.
B) have resistance to the action of penicillinase.
C) are semisynthetic.
D) have an expanded spectrum of activity.
E) All of the choices are correct.

F) A) and B)
G) None of the above

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Ciprofloxacin is used to treat viral respiratory infections.

A) True
B) False

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Which antimicrobial does not inhibit cell wall synthesis?


A) gentamicin
B) vancomycin
C) cephalosporins
D) penicillins
E) bacitracin

F) B) and E)
G) B) and D)

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Which drug is used to treat cases of tuberculosis?


A) penicillin G
B) vancomycin
C) tetracycline
D) synercid
E) isoniazid

F) None of the above
G) B) and D)

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Sulfonamides


A) interfere with elongation of peptidoglycan.
B) block folic acid synthesis.
C) attach to the 30S ribosomal subunit and disrupt protein synthesis.
D) damage cell membranes.
E) block peptidases that cross-link glycan molecules.

F) A) and B)
G) A) and C)

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Each of the following target bacterial ribosomes except


A) streptomycin.
B) gentamycin.
C) polymyxins.
D) tetracycline.
E) erythromycin.

F) All of the above
G) C) and D)

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Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. A 12-year-old male is admitted to the pediatric unit due to persistent upper respiratory symptoms and respiratory distress. The patient has a history of developmental delay, chronic lung disease, and frequent respiratory infections. Upon assessment, as the RN, you note the patient to have a fever, moderate respiratory rate, productive cough, and large amount of nasal secretions. Upon report from the patient’s mother, the patient has been on a 3-week course of antibiotics with no improvement in symptoms. Upon further workup, the patient is diagnosed with bacterial pneumonia and methicillin-resistant Staphylococcus aureus (MRSA) superinfection. -Based upon the patient's history,what is the most likely cause of the superinfection?


A) poor hygiene
B) long-term antibiotic therapy
C) fecal-oral contamination
D) community-acquired MRSA

E) All of the above
F) A) and B)

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Which of the following is not true of polymyxins?


A) disrupt the cell membrane
B) have a narrow spectrum
C) toxic to kidneys
D) target cell walls
E) can treat severe urinary tract infections

F) A) and B)
G) A) and C)

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Which of the following antibacterial drug groups does not target protein synthesis?


A) clindamycin
B) erythromycin
C) aminoglycosides
D) sulfonamides
E) tetracycline

F) D) and E)
G) All of the above

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Bacteria can have a natural resistance to a drug that it has never been exposed to.

A) True
B) False

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An antibiotic of the penicillin family is penicillin G.

A) True
B) False

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A superinfection results from


A) buildup of a drug to toxic levels in the patient.
B) the wrong drug administered to the patient.
C) an immune system reaction to the drug.
D) decrease in most normal flora with overgrowth of an unaffected species.
E) All of the choices are correct.

F) B) and C)
G) A) and D)

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Antimicrobials that are effective against a wide variety of microbial types are termed


A) antibiotics.
B) narrow-spectrum drugs.
C) semisynthetic drugs.
D) synthetic drugs.
E) broad-spectrum drugs.

F) B) and E)
G) A) and C)

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Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. A 12-year-old male is admitted to the pediatric unit due to persistent upper respiratory symptoms and respiratory distress. The patient has a history of developmental delay, chronic lung disease, and frequent respiratory infections. Upon assessment, as the RN, you note the patient to have a fever, moderate respiratory rate, productive cough, and large amount of nasal secretions. Upon report from the patient’s mother, the patient has been on a 3-week course of antibiotics with no improvement in symptoms. Upon further workup, the patient is diagnosed with bacterial pneumonia and methicillin-resistant Staphylococcus aureus (MRSA) superinfection. -You provide education to the patient and his mother regarding the diagnosis.Which of the following statements,by the mother,demonstrates an understanding of the teaching?


A) "My son has an extremely resistant form of MRSA causing his prolonged illness."
B) "My son developed simultaneous bacterial infections."
C) "My son developed a MRSA superinfection,following suppression of normal resident species in his lungs due to his initial infection."
D) "My son has pneumonia caused by a virus."

E) A) and B)
F) A) and C)

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Clavulanic acid


A) inhibits B-lactamase activity.
B) inhibits peptidoglycan synthesis.
C) inhibits formation of peptidoglycan cross linkages.
D) inhibits cell membrane synthesis.
E) None of the choices is correct.

F) B) and E)
G) A) and B)

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Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. A 76-year-old male visits his primary care physician with complaints of burning with urination and a frequent urge to void. As the RN, you aid the patient in collecting a urine specimen to be sent for analysis. While awaiting the final results of drug susceptibility testing in the lab, the patient is prescribed oral sulfasoxazole. -You provide education to the patient regarding sulfasoxazole,a sulfonamide that targets folic acid synthesis.The synthesis of which of the following products is affected by inhibition of folate metabolism?


A) DNA
B) RNA
C) DNA and RNA
D) DNA,RNA,and amino acids

E) B) and C)
F) A) and C)

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The drug that can cause injury to red blood cells and white blood cells is


A) chloramphenicol.
B) clindamycin.
C) ciprofloxacin.
D) bacitracin.
E) gentamicin.

F) A) and E)
G) A) and C)

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Drug susceptibility testing determines


A) the patient's response to various antimicrobials.
B) the pathogen's response to various antimicrobials.
C) if normal flora will be affected by antimicrobials.
D) if the drug is increasing to toxic levels in a patient.
E) None of the choices is correct.

F) C) and D)
G) A) and D)

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Each of the following affect cell walls except


A) penicillin.
B) isoniazid.
C) vancomycin.
D) erythromycin.
E) cephalosporin.

F) B) and E)
G) B) and D)

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What type of chemical will allow some bacteria to be resistant to many penicillins?


A) synercid
B) penicillinase
C) aztreonam
D) clavulanic acid
E) imipenem

F) None of the above
G) A) and D)

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