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Which of the following pertains to both tetanus and foodborne botulism?


A) Treatment involves antitoxin therapy.
B) An exotoxin blocks acetylcholine release.
C) Nausea and diarrhea are symptoms.
D) They occur when endospore-contaminated soil enters deep wounds.
E) They are caused by enterotoxins of the pathogen.

F) All of the above
G) A) and C)

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The expected outcome of an oxidase test performed to identify Neisseria menigitidis is


A) the amplification of the oxi gene as detected on an agarose gel.
B) cells colored black when stained and viewed under the microscope.
C) the appearance of bubbles when cells are mixed with hydrogen peroxide.
D) a zone of clearing surrounding colonies on chocolate agar.
E) a color change of a colony from tan to black when oxidase reagent is added.

F) All of the above
G) C) and E)

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Place the following components of the nervous system anatomy in order from skull to brain.


A) Pia mater, arachnoid mater, subarachnoid space, dura mater
B) Subarachnoid space, arachnoid mater, dura mater, pia mater
C) Dura mater, arachnoid mater, subarachnoid space, pia mater
D) Arachnoid mater, subarachnoid space, dura mater, pia mater
E) Dura mater, arachnoid mater, pia mater, subarachnoid space

F) C) and E)
G) None of the above

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Your friend was bitten by an aggressive dog with a history of biting without cause,and it is suspected to have rabies.The city health department recommends the rabies vaccination,even though she has already been exposed to the infectious agent.Which statement best describes why the vaccine can be given post-exposure?


A) There were few virus particles in the bite, so her immune system has enough time to respond.
B) Since there is no treatment available, they suggest the vaccine as a last resort.
C) The virus exhibits a long incubation period, and therefore, in many cases, this provides the vaccine adequate time to have a protective effect in the patient.
D) This particular strain of the rabies virus is probably nonpathogenic, so the vaccine is given to boost the immune system's protective functions.

E) C) and D)
F) B) and D)

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Neisseria meningitidis is transmitted by ______.


A) an insect vector
B) sexual contact
C) fomites
D) close contact

E) A) and B)
F) C) and D)

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What is the likelihood that a patient infected by West Nile virus will develop West Nile encephalitis?


A) Less than 1%
B) Between 1% and 10%
C) Between 10% and 15%
D) Greater than 20%
E) Greater than 50%

F) D) and E)
G) B) and C)

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Which type of cell has phagocytic capabilities in the central nervous system?


A) Macrophages
B) Neurons
C) Astrocytes
D) Schwann cells
E) Microglial cells

F) A) and B)
G) A) and C)

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What organism is the main reservoir and host for Toxoplasma gondii?


A) Mouse
B) Mosquito
C) Cat
D) Raccoon
E) Dog

F) D) and E)
G) A) and B)

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Which of the following statements about rabies is incorrect?


A) Transmission can involve bites, scratches, and inhalation.
B) Rabies is a zoonotic disease.
C) Symptoms include anxiety, agitation, muscle spasms, convulsions, and paralysis.
D) The average incubation period in human is 1 week.
E) Wild populations of bats, skunks, raccoons, cats, and canines are primary reservoirs.

F) B) and E)
G) None of the above

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Agricultural workers and field archaeologists are exposed to this organism which,despite entering via the respiratory tract,can cause meningitis.


A) Cryptococcus neoformans
B) Haemophilus influenzae
C) Streptococcus pneumoniae
D) Coccidioides immitis
E) Neisseria meningitidis

F) A) and E)
G) A) and C)

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Botulism is often referred to as lockjaw.

A) True
B) False

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The vector involved in African sleeping sickness is the ______.


A) tsetse fly
B) reduviid "kissing" bug
C) sand fly
D) hard-bodied tick
E) Anopheles mosquito

F) B) and D)
G) B) and E)

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Two nervous system diseases are food-borne,botulism caused by Clostridium botulinum and listeriosis,a form of meningitis,caused by Listeria monocytogenes.These diseases differ in that


A) botulism has a very high mortality rate (~50%) , whereas listeriosis is readily cured by a course of antibiotics.
B) botulism results from an intoxication, whereas listeriosis is an infection.
C) listeriosis primarily affects pregnant women, whereas botulism can affect anyone.
D) listeriosis is associated with contaminated low-acid vegetables, whereas botulism is associated with contaminated infant formula.

E) C) and D)
F) A) and C)

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The organism responsible for the majority of neonatal meningitis is ______.


A) Listeria monocytogenes
B) Streptococcus agalactiae
C) Neisseria meningitidis
D) Haemophilus influenzae
E) Escherichia coli K1

F) None of the above
G) C) and D)

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Production of a neurotoxin that binds to target sites on spinal cord neurons responsible for inhibiting skeletal muscle contraction is a characteristic of ______.


A) Clostridium tetani
B) Clostridium botulinum
C) Clostridium difficile
D) Clostridium perfringens

E) None of the above
F) A) and D)

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Which of the following is/are a sign or symptom of meningitis?


A) Headache
B) Stiff neck
C) White blood cells in cerebrospinal fluid
D) Fever
E) All of the choices are correct.

F) A) and D)
G) A) and C)

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Toxoplasmosis prevention includes ______.


A) vector control
B) hygienic precautions
C) vaccination of humans
D) vaccination of cats

E) A) and B)
F) A) and D)

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The normal biota of the central nervous system includes ______.


A) Neisseria meningitidis
B) Herpes simplex I
C) Herpes simplex II
D) Streptococcus agalactiae
E) The CNS has no normal biota.

F) C) and D)
G) B) and E)

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Botox injections contain botulinum toxin.

A) True
B) False

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Prions can be destroyed by autoclaving.

A) True
B) False

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