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Careful measurements of GFR are made by injection of ________, but approximations of GFR can be made more simply by measuring renal plasma clearance of ________.


A) creatine phosphate; insulin
B) insulin; creatine phosphate
C) inulin; creatinine
D) creatinine; inulin

E) B) and C)
F) A) and D)

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Type A and Type B cells of kidney tubules are types of principal cells.

A) True
B) False

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Which of the following is a nitrogenous waste product produced from nucleic acid breakdown in the liver?


A) Urea
B) Deoxyribose
C) Uric acid
D) Creatinine

E) A) and C)
F) A) and B)

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The kidneys are located ________ the peritoneum.


A) within
B) anterior to
C) posterior to

D) A) and B)
E) A) and C)

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The diffusion of urea out of the distal convoluted tubule is an important part of maintaining the concentration gradient of the renal medulla.

A) True
B) False

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The juxtaglomerular apparatus is located


A) within the renal sinus.
B) in the renal papilla.
C) in the perinephric fat.
D) inside the tubular pole of the glomerulus.
E) near the vascular pole of the renal corpuscle.

F) A) and E)
G) None of the above

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Collecting ducts are larger than collecting tubules.

A) True
B) False

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During prolonged fasting, the kidneys produce glucose from noncarbohydrate sources.

A) True
B) False

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Generally, the higher the renal plasma clearance of a given drug, the more frequently the drug must be given in order to be effective.

A) True
B) False

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Macula densa cells signal granular cells to release renin through paracrine stimulation.

A) True
B) False

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Stimulation of granular cells by the sympathetic nervous system causes them to


A) contract.
B) relax.
C) release calcitriol.
D) increase endocytosis.

E) A) and B)
F) A) and C)

Correct Answer

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As it is leaving the kidney, blood passes directly from the arcuate vein to the


A) renal vein.
B) vasa recta.
C) segmental vein.
D) interlobar vein.
E) interlobular vein.

F) A) and D)
G) A) and C)

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Which is not correct regarding the innervation of the kidney?


A) Parasympathetic innervation is from the vagus nerve.
B) The kidney is served by the renal plexus.
C) Sympathetic innervation is from segments T10-T12 of the spinal cord.
D) Sympathetic stimulation causes vasoconstriction of the renal blood vessels.
E) Parasympathetic stimulation decreases the rate of filtrate formation.

F) A) and E)
G) A) and D)

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Select all that have regulated reabsorption.


A) Glucose
B) Sodium
C) Water
D) Calcium

E) All of the above
F) A) and B)

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The specific gravity of urine is its density compared to that of water, and the more solutes urine has, the higher its specific gravity.

A) True
B) False

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Both aspirin and morphine are eliminated in the urine.

A) True
B) False

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The renal threshold of a substance refers to


A) the number of protein transporters for the substance per tubule.
B) the plasma concentration of the substance below which it does not appear in the urine.
C) the concentration of the substance found in the kidney before the substance becomes toxic.
D) the concentration of the substance in the urine that results in an overall increase in urine volume.

E) A) and C)
F) A) and D)

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Gross & microscopic anatomy of the urinary tract, including detailed histology of the nephron. Gross & microscopic anatomy of the urinary tract, including detailed histology of the nephron.   -This figure shows a frontal section of the kidney. Which number(s)  indicate a renal papilla? A)  2, 7 B)  3 C)  6 D)  9 E)  10 -This figure shows a frontal section of the kidney. Which number(s) indicate a renal papilla?


A) 2, 7
B) 3
C) 6
D) 9
E) 10

F) A) and C)
G) D) and E)

Correct Answer

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The reabsorption of both sodium and potassium is carefully regulated.

A) True
B) False

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The glomerulus is part of the renal tubule.

A) True
B) False

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