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A xenograft is graft tissue from a donor of one species transplanted to a recipient of another species.

A) True
B) False

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The patient discusses his antirejection medication regiment with the nurse. He asks how they work to prevent graft rejection. What is the best explanation by the RN?


A) Antirejection medications work on your liver to make it less hostile to its new environment, increasing the chances of organ acceptance.
B) Antirejection medications work by changing the MHC markers on your new liver to be more like your own.
C) Antirejection medications work by suppressing the body's immune response against foreign MHC markers.
D) Antirejection medications work by causing your body to think its MHC markers are similar to your new liver's.

E) A) and B)
F) B) and D)

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Bee sting venom is considered to be which type of allergen?


A) Ingestant
B) Inhalant
C) Injectant
D) Contactant
E) None of the choices are correct.

F) D) and E)
G) A) and B)

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A seasonal reaction to inhaled allergens is ________.


A) atopic dermatitis
B) eczema
C) allergic rhinitis
D) asthma
E) anaphylaxis

F) A) and B)
G) B) and C)

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Allergies run in families because ________.


A) immunoglobulins pass from mother to fetus
B) immunoglobulins pass through breast milk
C) the variable region of antibodies is genetically determined
D) relative production of IgE is inherited
E) All of the choices are correct.

F) B) and D)
G) A) and E)

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Histamine causes all of the following except ________.


A) increased sensitivity to pain
B) constriction of smooth muscle of bronchi and the intestine
C) relaxes vascular smooth muscle
D) wheal and flare reaction in skin
E) pruritus and headache

F) D) and E)
G) A) and D)

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Allergic reactions to penicillins are considered a(n) ________ hypersensitivity.


A) T-cell mediated
B) antibody mediated
C) immune complex mediated
D) immediate
E) both T-cell mediated and antibody mediated

F) A) and D)
G) A) and E)

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Human blood types involve all the following except ________.


A) MHC genes
B) ABO antigen markers
C) inheritance of two of three possible alleles
D) genetically determined glycoprotein markers
E) genes that code for an enzyme that adds a terminal carbohydrate to RBC receptors

F) C) and E)
G) A) and B)

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Corticosteroids will ________.


A) inhibit the activity of lymphocytes
B) bind to histamine receptors on target organs
C) block synthesis of leukotrienes
D) relieve inflammatory symptoms
E) reverse spasms of respiratory smooth muscles

F) B) and D)
G) A) and B)

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Transfusion of the wrong blood type can cause ________.


A) recipient antibody activating the complement cascade to attack the RBCs
B) fever and anemia
C) systemic shock and kidney failure
D) massive hemolysis of the donor RBCs
E) All of the choices are correct.

F) None of the above
G) C) and D)

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Asthma is classified as what type of reaction?


A) Atopy
B) Systemic anaphylaxis
C) Acute allergic
D) Cutaneous anaphylaxis

E) B) and D)
F) All of the above

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What type of hypersensitivity reaction is an organ transplantation patient at risk for?


A) Type I
B) Type II
C) Type III
D) Type IV

E) All of the above
F) B) and C)

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What type of transplant did the patient receive?


A) Isograft
B) Autograft
C) Allograft
D) Xenograft

E) A) and C)
F) A) and B)

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Epinephrine ________.


A) is an antihistamine
B) reverses constriction of airways
C) causes desensitization
D) inhibits the activity of lymphocytes
E) All of the choices are correct.

F) B) and C)
G) All of the above

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Degranulation of mast cells leads to ________.


A) airway obstruction
B) headache
C) dilated blood vessels
D) All of the choices are correct.

E) A) and D)
F) A) and C)

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Each of the following is an autoimmune disease except ________.


A) systemic lupus erythematosus
B) Graves' disease
C) type I diabetes
D) metastatic cancer
E) rheumatic fever

F) None of the above
G) C) and D)

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All of the following are associated with IgE and mast cell-mediated allergy except ________.


A) drug allergy
B) eczema
C) anaphylaxis
D) allergic asthma
E) systemic lupus erythematosus

F) A) and D)
G) A) and C)

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The tuberculin reaction develops within 30 minutes of the skin test in people with prior sensitization due to tuberculosis infection.

A) True
B) False

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In the theory for allergic desensitization, which immunoglobulin blocks the allergen from binding with IgE?


A) IgE
B) IgG
C) IgA
D) IgD
E) IgM

F) A) and E)
G) C) and D)

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A female who is Rh- ________.


A) inherited two dominant genes
B) is in the majority of the population with regard to Rh status
C) is at risk for a pregnancy resulting in hemolytic disease of the newborn
D) can never have an Rh+ baby
E) All of the choices are correct.

F) A) and E)
G) D) and E)

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