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What is the site of longitudinal growth in long bones?


A) epiphyseal plate
B) epiphysis
C) medullary cavity
D) Sharpey's fibers
E) endosteum

F) A) and C)
G) A) and B)

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Collagen and calcium hydroxyapatite are the primary constituents of


A) bone matrix.
B) blood.
C) fibrous cartilage.
D) hyaline cartilage.
E) ligaments.

F) A) and E)
G) B) and E)

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Which type of bone cells possess extensive ER and ribosomes?


A) osteocytes
B) osteoblasts
C) osteoclasts
D) osteochondral progenitor cell

E) All of the above
F) A) and B)

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What strengthens the attachment of the tendons or ligaments to bone?


A) growth plate
B) epiphysis
C) Sharpey fibers
D) medullary cavity
E) endosteum

F) None of the above
G) A) and D)

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A bone fracture in which the two bone sections do not separate is a(an)


A) closed fracture.
B) hairline fracture.
C) open fracture.
D) impaction fracture.
E) comminuted fracture.

F) A) and B)
G) A) and C)

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Which of the following occurs in the formation of mineralized bone matrix?


A) Blood calcium is elevated.
B) Hydrogen ions form an acid environment in bone matrix.
C) Ca2+ is actively transported from bone matrix to the blood.
D) The protein components of bone matrix are digested.
E) Osteoblasts form collagen and proteoglycans.

F) A) and D)
G) A) and C)

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The type of lamellae found in osteons (Haversian systems) is


A) circumferential.
B) interstitial.
C) appositional.
D) concentric.
E) oppositional.

F) B) and E)
G) C) and D)

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An example of a long bone would be


A) the sternum.
B) the tibia.
C) a rib.
D) the clavicle.
E) a carpal bone.

F) None of the above
G) B) and E)

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Which type of bone cells package calcium and phosphate ions?


A) osteochondral progenitor cell
B) osteoclasts
C) osteoblasts
D) osteocytes

E) B) and D)
F) A) and B)

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Bone growth of the epiphysis occurs at the


A) diaphysis.
B) joint cavity.
C) epiphyseal plate.
D) perichondrium.
E) articular cartilage.

F) B) and D)
G) A) and E)

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Define basic multicellular unit (BMU) .


A) The clusters of chondrocytes within the metaphysis that will be converted to bone
B) A group of osteoblasts and osteoclasts that work together during bone remodeling
C) The osteoblasts found in the deepest layer of the periosteum,involved in appositional growth

D) All of the above
E) B) and C)

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When blood calcium levels are low


A) ostoclast activity increases.
B) calcitonin secretion increases.
C) bones produce more bone tissue.
D) calcium absorption is reduced.
E) osteoblast activity increases.

F) B) and E)
G) A) and E)

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Which type of bone cells have processes that lie in canaliculi?


A) osteocytes
B) osteoblasts
C) osteoclasts
D) osteochondral progenitor cell

E) C) and D)
F) B) and D)

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Chondroblasts produce


A) ligaments.
B) blood cells.
C) bone tissue.
D) cartilage matrix.
E) synovial fluid.

F) A) and B)
G) A) and C)

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The processes of intramembranous and endochondral ossification are similar in several respects.Which of the following statements applies to both intramembranous and endochondral ossification?


A) Both processes require a precursor of connective tissue membranes.
B) Both processes form woven bone.
C) Both only form flat bones.
D) Chondrocytes participate in both processes.
E) In both processes,bone replaces cartilage.

F) All of the above
G) A) and B)

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The primary mineral in bone is


A) iron.
B) sodium.
C) potassium.
D) calcium.
E) oxygen.

F) A) and E)
G) A) and C)

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Miguel falls out of a tree and breaks his fall by putting his arm out,fracturing his radius and ulna.What specific type of bone fracture is Miguel most likely to have?


A) dentate fracture
B) impaction fracture
C) spiral fracture
D) complicated fracture
E) none of these

F) A) and B)
G) A) and C)

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Which of the following is NOT an effect of parathyroid hormone (PTH) ?


A) increased Ca2+ uptake by the small intestine
B) increased vitamin D formation in the kidneys
C) increased Ca2+ reabsorption by the kidneys
D) decreased Ca2+ loss by the kidneys
E) All of these are effects of PTH.

F) A) and B)
G) A) and E)

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What effects can be attributed to increased pressure on a bone?


A) increased osteoclast activity
B) increased osteoblast activity

C) A) and B)
D) undefined

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Brittle bone disorder is another name for


A) scurvy.
B) osteomyelitis.
C) osteoporosis.
D) osteomalacia.
E) osteogenesis imperfecta.

F) None of the above
G) C) and D)

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